Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.31 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.31 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634855 | 1.00 | ACKR3 (0.35) | ACKR3CCR5ALOX5MEN1KMT2A | |
| SCHEMBL4120631 | 0.80 | — | — | |
| SCHEMBL4133696 | 0.78 | MEN1 (0.37) | ACKR3CCR5ALOX5MEN1KMT2A | |
| SCHEMBL4133702 | 0.78 | MEN1 (0.37) | ACKR3CCR5ALOX5MEN1KMT2A | |
| SCHEMBL4141062 | 0.78 | PTPN1 (0.42) | ALOX5MEN1KMT2APTPN1RAB9A | |
| SCHEMBL4141057 | 0.78 | PTPN1 (0.42) | ALOX5MEN1KMT2APTPN1RAB9A | |
| SCHEMBL4134054 | 0.77 | ALOX5 (0.37) | ALOX5MEN1KMT2APTPN1RAB9A | |
| SCHEMBL4134057 | 0.77 | ALOX5 (0.37) | ALOX5MEN1KMT2APTPN1RAB9A | |
| SCHEMBL4125487 | 0.76 | ALOX5 (0.38) | ALOX5MEN1KMT2ARAB9ACISD1 | |
| SCHEMBL4125493 | 0.76 | ALOX5 (0.38) | ALOX5MEN1KMT2ARAB9ACISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | claimed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | claimed |