⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634855 | 0.80 | ACKR3 (0.35) | — | |
| SCHEMBL4634853 | 0.80 | ACKR3 (0.35) | — | |
| SCHEMBL4133696 | 0.59 | MEN1 (0.37) | — | |
| SCHEMBL4133702 | 0.59 | MEN1 (0.37) | — | |
| SCHEMBL27856823 | 0.55 | ALDH1A1 (0.62) | — | |
| SCHEMBL6385141 | 0.54 | S1PR1 (0.39) | — | |
| SCHEMBL27608722 | 0.53 | TYR (0.38) | — | |
| SCHEMBL1533205 | 0.53 | ALDH1A1 (0.62) | — | |
| SCHEMBL5853821 | 0.53 | RAB9A (0.47) | — | |
| SCHEMBL12500530 | 0.52 | MAPT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088432-A1 | Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors | TORRENT PHARMACEUTICALS LIMITED (IN) | 2009-04-02 | — | — | US | claimed |
| US-20090088432-A1 | Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors | TORRENT PHARMACEUTICALS LIMITED (IN) | 2009-04-02 | — | — | US | disclosed |