Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | MPL | P40238 | 2/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634945 | 1.00 | PDE2A (0.44) | PDE2AIDO1MPLPTPN5APP | |
| SCHEMBL20231081 | 0.83 | PDE2A (0.42) | PDE2AIDO1MPLPTPN5APP | |
| SCHEMBL11883532 | 0.78 | HTR3E (0.53) | PDE2AIDO1MPLPTPN5APP | |
| SCHEMBL29755384 | 0.78 | PDE2A (0.44) | PDE2AIDO1MPLPTPN5APP | |
| SCHEMBL18321910 | 0.78 | PDE2A (0.44) | PDE2AIDO1MPLPTPN5APP | |
| SCHEMBL2278837 | 0.78 | PDE2A (0.39) | PDE2AIDO1MPLPTPN5APP | |
| SCHEMBL4635226 | 0.76 | PDE2A (0.47) | PDE2APTPN5GAAMEN1LMNA | |
| SCHEMBL4635224 | 0.76 | PDE2A (0.47) | PDE2APTPN5GAAMEN1LMNA | |
| SCHEMBL2147584 | 0.75 | PDE2A (0.50) | PDE2AIDO1MPLPTPN5GAA | |
| SCHEMBL29827588 | 0.75 | PDE2A (0.50) | PDE2AIDO1MPLPTPN5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1524261-B1 | Process for preparing fluorinated anilines | SALTIGO GMBH (DE) | 2008-06-11 | — | — | EP | claimed |
| US-7154006-B2 | Preparation of fluorinated anilines | BAYER AKTIENGESELLSCHAFT (DE) | 2006-12-26 | — | — | US | claimed |
| US-20050101795-A1 | Preparation of fluorinated anilines | BAYER CHEMICALS AG | 2005-05-12 | — | — | US | claimed |
| US-7154006-B2 | Preparation of fluorinated anilines | BAYER AKTIENGESELLSCHAFT (DE) | 2006-12-26 | — | — | US | disclosed |
| US-20050101795-A1 | Preparation of fluorinated anilines | BAYER CHEMICALS AG | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101795-A1 | Preparation of fluorinated anilines | FLNA, FLNB, FLI1 | PDE2A 2730/4885IDO1 721/4885MPL 2497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.