SCHEMBL4635144

SCHEMBL4635144

[O-][n+]1ccccc1-c1nnc(-c2cccc[n+]2[O-])nn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 4/20 0.35
NPC1 O15118 3/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ABCC9 O60706 1/20 0.31
ABCC8 Q09428 1/20 0.31
KCNJ11 Q14654 1/20 0.31
KCNJ8 Q15842 1/20 0.31
MAPT P10636 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
KAT6A Q92794 1/20 0.30
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29727517 0.82 LMNA (0.52) LMNAHTTRAB9ANPC1KMT2A
SCHEMBL871319 0.82 LMNA (0.52) LMNAHTTRAB9ANPC1KMT2A
SCHEMBL11777157 0.78 LMNA (0.32) LMNAHTT
SCHEMBL27684655 0.77 LMNA (0.48) LMNAHTTRAB9ANPC1KMT2A
SCHEMBL30404171 0.76 LMNA (0.35) LMNAHTT
SCHEMBL11755861 0.74 ABCC9 (0.30) ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL316983 0.73 HTT (0.44) LMNAHTTRAB9ANPC1MAPK1
SCHEMBL31088294 0.73 HTT (0.44) LMNAHTTRAB9ANPC1MAPK1
SCHEMBL8755109 0.73 LMNA (0.40) LMNAHTTRAB9AMAPK1KMT2A
SCHEMBL31509682 0.73 LMNA (0.40) LMNAHTTRAB9AMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1597310-B1 ABSORBENT MATERIAL FOR USE IN HUMID CONDITIONS COMMW SCIENT IND RES ORG (AU) 2008-06-18 EP claimed
US-20060263502-A1 Absorbent material for use in humid conditions COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH INSTITUTE (AU) 2006-11-23 US claimed
EP-1597310-B1 ABSORBENT MATERIAL FOR USE IN HUMID CONDITIONS COMMW SCIENT IND RES ORG (AU) 2008-06-18 EP disclosed
US-20060263502-A1 Absorbent material for use in humid conditions COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH INSTITUTE (AU) 2006-11-23 US disclosed
EP-1597310-A4 ABSORBENT MATERIAL FOR USE IN HUMID CONDITIONS COMMW SCIENT IND RES ORG (AU) 2006-11-02 EP disclosed
EP-1597310-A1 ABSORBENT MATERIAL FOR USE IN HUMID CONDITIONS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2005-11-23 EP disclosed
WO-2004076545-A1 ABSORBENT MATERIAL FOR USE IN HUMID CONDITIONS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-09-10 WO disclosed