Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.57 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | TPO | P07202 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635524 | 0.88 | SSTR5 (0.44) | KCNH2NR4A2SSTR5MEN1POLB | |
| SCHEMBL3970572 | 0.81 | KCNH2 (0.42) | KCNH2NR4A2SOS1MPOTPO | |
| SCHEMBL3971456 | 0.80 | HTR6 (0.39) | KCNH2NR4A2SOS1MPOTPO | |
| Bromide SCHEMBL9564852 | 0.80 | KCNH2 (0.57) | KCNH2NR4A2SOS1SSTR5MEN1 | |
| Bromide SCHEMBL9699462 | 0.76 | KCNH2 (0.72) | KCNH2NR4A2SOS1SSTR5MEN1 | |
| Hydrochloric Acid SCHEMBL9630081 | 0.73 | KCNH2 (0.67) | KCNH2NR4A2SOS1SSTR5MEN1 | |
| Tecastemizole SCHEMBL18200 | 0.72 | KCNH2 (1.00) | KCNH2NR4A2SOS1SSTR5MEN1 | |
| Tecastemizole SCHEMBL9698437 | 0.72 | KCNH2 (0.98) | KCNH2NR4A2SOS1SSTR5MEN1 | |
| Bromide SCHEMBL11304724 | 0.72 | KCNH2 (0.78) | KCNH2NR4A2SOS1SSTR5MEN1 | |
| Tecastemizole SCHEMBL11278980 | 0.72 | KCNH2 (0.98) | KCNH2NR4A2SOS1SSTR5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532150-B1 | NOVEL PURINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-06-11 | — | — | EP | claimed |