Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 7/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | EED | O75530 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HLA-A | P04439 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635252 | 0.88 | KCNH2 (0.57) | SSTR5KCNH2NR4A2MEN1KMT2A | |
| SCHEMBL3971451 | 0.82 | GAA (0.40) | KCNH2POLBSMN1; SMN2GAAHRH1 | |
| SCHEMBL9564924 | 0.80 | KCNH2 (0.47) | SSTR5KCNH2NR4A2MEN1KMT2A | |
| SCHEMBL10057014 | 0.75 | P2RX3 (0.56) | SSTR5KCNH2NR4A2MEN1KMT2A | |
| SCHEMBL3971456 | 0.73 | HTR6 (0.39) | KCNH2NR4A2POLBSMN1; SMN2LMNA | |
| SCHEMBL10529762 | 0.72 | SSTR5 (0.78) | SSTR5KCNH2NR4A2MEN1KMT2A | |
| SCHEMBL11480609 | 0.72 | SSTR5 (0.57) | SSTR5KCNH2NR4A2MEN1KMT2A | |
| SCHEMBL3970572 | 0.71 | KCNH2 (0.42) | KCNH2NR4A2LMNAGAATP53 | |
| SCHEMBL9631566 | 0.70 | CYP1A2 (0.50) | SSTR5KCNH2NR4A2MEN1KMT2A | |
| SCHEMBL13199901 | 0.70 | POLB (0.50) | MEN1KMT2APOLBTP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532150-B1 | NOVEL PURINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-06-11 | — | — | EP | claimed |