SCHEMBL4635319

SCHEMBL4635319

CC(C)OC(=O)c1ccc(O)cc1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC28A3 Q9HAS3 6/20 0.55
AKR1B1 P15121 1/20 0.53
DPP4 P27487 1/20 0.53
TYR P14679 4/20 0.52
SLC5A1 P13866 3/20 0.50
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
SLC5A2 P31639 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
THRB P10828 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
SLC28A2 O43868 1/20 0.50
EPHX2 P34913 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4635939 0.91 AKR1B1 (0.53) SLC28A3AKR1B1DPP4TYRSLC5A1
SCHEMBL4635920 0.87 SLC28A3 (0.58) SLC28A3AKR1B1DPP4TYRHPGD
SCHEMBL4636284 0.86 NPC1 (0.64) SLC28A3AKR1B1DPP4TYRKDM4E
SCHEMBL4635348 0.85 SLC28A3 (0.56) SLC28A3AKR1B1DPP4TYRSLC5A1
SCHEMBL4635767 0.83 TYR (0.59) SLC28A3AKR1B1DPP4TYRSLC5A1
SCHEMBL4636214 0.83 SLC28A3 (0.56) SLC28A3AKR1B1DPP4TYRSLC5A1
SCHEMBL7780208 0.83 SLC28A3 (0.50) SLC28A3AKR1B1DPP4TYRSLC5A1
SCHEMBL941797 0.82 SLC28A3 (0.58) SLC28A3TYRSLC5A1SLC5A2
SCHEMBL7781036 0.82 SLC28A3 (0.49) SLC28A3AKR1B1DPP4TYRSLC5A1
SCHEMBL941369 0.81 NPC1 (0.56) AKR1B1DPP4TYRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1932514-B1 PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR EZAKI GLICO CO (JP) 2018-11-14 EP disclosed
US-20140023602-A1 EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE EZAKI GLICO CO., LTD. (JP) 2014-01-23 US disclosed
US-20080274068-A1 External Preparation for Skin Containing a Phosphorlated Saccharide EZAKI GLICO CO., LTD. (JP) 2008-11-06 US disclosed
EP-1932514-A1 PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR Ezaki Glico Co., Ltd. (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140023602-A1 EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE SI, CUTA, CD44 SLC28A3 1164/4885AKR1B1 3154/4885DPP4 3179/4885
US-20080274068-A1 External Preparation for Skin Containing a Phosphorlated Saccharide CUTA, SI, CD44 SLC28A3 977/4885AKR1B1 3102/4885DPP4 3158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.