Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LATS1 | O95835 | 3/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704061 | 0.93 | LATS1 (0.43) | MEN1KMT2ALMNAPOLBLATS1 | |
| SCHEMBL1704731 | 0.85 | CYP3A4 (0.43) | MEN1KMT2ALMNAPOLBLATS1 | |
| SCHEMBL2953212 | 0.85 | LATS1 (0.43) | MEN1KMT2ALMNAPOLBLATS1 | |
| SCHEMBL1704446 | 0.85 | MAPK1 (0.44) | MEN1KMT2ALMNAPOLBLATS1 | |
| SCHEMBL2950038 | 0.84 | KMT2A (0.46) | MEN1KMT2ALMNAPOLBNAMPT | |
| SCHEMBL4452111 | 0.84 | LATS1 (0.42) | MEN1KMT2ALATS1NAMPTLATS2 | |
| SCHEMBL1705388 | 0.84 | RAB9A (0.43) | MEN1KMT2ALMNAPOLBLATS1 | |
| SCHEMBL2956022 | 0.83 | MEN1 (0.46) | MEN1KMT2ALMNAPOLBLATS1 | |
| SCHEMBL2952980 | 0.81 | CCNC (0.42) | MEN1KMT2ALMNAPOLBLATS1 | |
| SCHEMBL2956044 | 0.80 | LATS1 (0.48) | MEN1KMT2ALMNAPOLBLATS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931642-A2 | NOVEL PYRIMIDINE CARBOXAMIDES | Orchid Research Laboratories Limited (IN) | 2008-06-18 | — | — | EP | claimed |
| WO-2007031829-A2 | NOVEL PYRIMIDINE CARBOXAMIDES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-22 | — | — | WO | claimed |