Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 12/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4339120 | 0.89 | PIK3CG (0.51) | PIK3CGMAPTTP53PIK3CD | |
| SCHEMBL4535440 | 0.84 | MAPT (0.49) | MAPTTP53PIK3CD | |
| SCHEMBL3690864 | 0.83 | PIK3CG (0.50) | PIK3CGMAPTTP53PIK3CD | |
| SCHEMBL4636003 | 0.83 | PIK3CA (0.56) | PIK3CGMAPTTP53PIK3CD | |
| SCHEMBL4337577 | 0.82 | MAPT (0.50) | PIK3CGMAPTTP53PIK3CD | |
| SCHEMBL4021236 | 0.79 | L3MBTL1 (0.55) | PIK3CGMAPTTP53 | |
| SCHEMBL4481357 | 0.78 | MAPT (0.50) | MAPTTP53 | |
| SCHEMBL4351831 | 0.78 | MEN1 (0.47) | MAPTTP53PIK3CD | |
| SCHEMBL2304665 | 0.76 | MAPT (0.52) | PIK3CGMAPTTP53 | |
| SCHEMBL4341730 | 0.75 | PIK3CD (0.49) | PIK3CGMAPTTP53PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931645-A2 | N- (3-AMINO-QUINOXALIN-2-YL) -SULFONAMIDE DERIVATIVES AND THEIR USE AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | Exelixis, Inc. (US) | 2008-06-18 | — | — | EP | claimed |
| WO-2007044729-A2 | N- (3-AMINO-QUINOXALIN-2-YL) -SULFONAMIDE DERIVATIVES AND THEIR USE AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | EXELIXIS, INC. (US) | 2007-04-19 | — | — | WO | claimed |