Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1814309 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1TDP1HPGD | |
| SCHEMBL3534757 | 0.84 | ALDH1A1 (0.43) | ALDH1A1CA12KMT2AMEN1TSHR | |
| SCHEMBL3531827 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CA12KMT2AMEN1HPGD | |
| SCHEMBL4635963 | 0.79 | HTT (0.39) | ALDH1A1CA12KMT2AMEN1L3MBTL1 | |
| SCHEMBL3529355 | 0.79 | HTT (0.71) | ALDH1A1CA12KMT2AMEN1TDP1 | |
| SCHEMBL3531657 | 0.78 | KMT2A (0.50) | ALDH1A1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL3538669 | 0.78 | HTT (0.39) | ALDH1A1CA12KMT2AMEN1CA1 | |
| SCHEMBL3531477 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1L3MBTL1NPY5R | |
| SCHEMBL10404597 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CA12KMT2AMEN1TSHR | |
| SCHEMBL3532841 | 0.77 | HTT (0.38) | ALDH1A1CA12KMT2AMEN1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931640-A2 | SUBSTITUTED-3-SULFONYLINDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | Wyeth a Corporation of the State of Delaware (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007021711-A2 | SUBSTITUTED-3-SULFONYLINDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2007-02-22 | — | — | WO | disclosed |