Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 6/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480241 | 0.67 | UTS2R (0.40) | KDM6BKDM4CHTR1AADRA1DADRA1A | |
| SCHEMBL16655234 | 0.66 | NR4A2 (0.32) | — | |
| SCHEMBL23074722 | 0.66 | HTR1A (0.44) | KDM6BKDM4CHTR1AADRA1DADRA1A | |
| SCHEMBL4636099 | 0.65 | PIM1 (0.39) | HCAR3PDE5AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23339882 | 0.63 | CYP1A2 (0.50) | HTR1AADRA1DADRA1AADRA1BUTS2R | |
| SCHEMBL18510377 | 0.63 | CDK1 (0.51) | NPC1KDM4E | |
| SCHEMBL8937938 | 0.63 | SLC29A1 (0.34) | UTS2RPDE5AALDH1A1SMN1; SMN2 | |
| SCHEMBL25476261 | 0.62 | NOS2 (0.47) | KDM6BKDM4CHTR1AADRA1DADRA1A | |
| SCHEMBL4142709 | 0.61 | HTR1A (0.80) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9180960 | 0.61 | HTT (0.57) | PDE5AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931620-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIQUIDS | Sanofi-Aventis (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007034252-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIQUIDS | SANOFI-AVENTIS (FR) | 2007-03-29 | — | — | WO | disclosed |