Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4150616 | 0.89 | RORC (0.39) | RORCDHODHTLR7FSCN1 | |
| SCHEMBL4141906 | 0.82 | RORC (0.43) | RORCTLR7 | |
| SCHEMBL4636222 | 0.81 | CES2 (0.35) | RORCDHODHCES2BCHECES1 | |
| SCHEMBL4151440 | 0.81 | RORC (0.34) | RORCTLR7GPBAR1 | |
| SCHEMBL4636412 | 0.80 | CES2 (0.34) | RORCCES2BCHECES1GPBAR1 | |
| SCHEMBL4166873 | 0.79 | RORC (0.36) | RORCTLR7 | |
| SCHEMBL4149997 | 0.78 | RORC (0.41) | RORCTLR7FSCN1 | |
| SCHEMBL4636721 | 0.77 | NPC1 (0.39) | RORCCES2BCHECES1 | |
| SCHEMBL4164252 | 0.76 | RORC (0.40) | RORCTLR7FSCN1 | |
| SCHEMBL4150885 | 0.76 | MEN1 (0.39) | RORCTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |