Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1638945 | 0.77 | TSHR (0.42) | POLBCA2CA4NPC1CA12 | |
| SCHEMBL3956783 | 0.72 | ALDH1A1 (0.53) | ALOX15CYP3A4POLBCA2CA4 | |
| SCHEMBL31117138 | 0.71 | INPPL1 (0.47) | GAAPOLBCA2KDM4EALDH1A1 | |
| SCHEMBL10869886 | 0.70 | CA2 (0.39) | GAAALOX15CYP3A4POLBCA2 | |
| SCHEMBL595587 | 0.69 | NR1H2 (0.39) | ALOX15CYP3A4CA2CA4CA5A | |
| SCHEMBL9574426 | 0.68 | ALDH1A1 (0.47) | ALOX15CYP3A4POLBCA2CA4 | |
| SCHEMBL9160401 | 0.68 | ALDH1A1 (0.47) | ALOX15CYP3A4POLBCA2CA4 | |
| SCHEMBL3068411 | 0.68 | HPGD (0.41) | CA2CA4CA5AKDM4EALDH1A1 | |
| SCHEMBL28576035 | 0.67 | GAA (0.37) | GAAALOX15CYP3A4POLBCA2 | |
| Pyrophosphoric Acid SCHEMBL31318897 | 0.66 | CA2 (0.53) | GAAALOX15CYP3A4POLBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883645-A4 | DERIVATIVES OF 4-OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC (US) | 2008-06-25 | — | — | EP | disclosed |
| EP-1883645-A1 | DERIVATIVES OF 4-OR 5-AMINOSALICYLIC ACID | Antibe Therapeutics Inc. (US) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006125295-A1 | DERIVATIVES OF 4-OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC. (CA) | 2006-11-30 | — | — | WO | disclosed |