Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 5/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4636043 | 0.80 | ADORA3 (0.48) | ADORA2BADORA3GLABLMMAOB | |
| SCHEMBL4637278 | 0.80 | ADORA2B (0.49) | ADORA2BADORA3GLABLMMAOB | |
| SCHEMBL4636230 | 0.79 | ADORA1 (0.48) | ADORA2BADORA3GLABLMMAOB | |
| SCHEMBL2538710 | 0.78 | ADORA2B (0.49) | ADORA2BADORA3GLABLMMAOB | |
| SCHEMBL4636557 | 0.78 | ADORA2B (0.46) | ADORA2BADORA3ADORA2A | |
| SCHEMBL3949936 | 0.76 | ADORA2B (0.59) | ADORA2BADORA3GLABLMADORA2A | |
| SCHEMBL2542700 | 0.76 | ADORA1 (0.49) | ADORA2BADORA3GLAMAOBADORA2A | |
| SCHEMBL2546553 | 0.75 | ADORA2B (0.47) | ADORA2BADORA3GLABLMADORA2A | |
| SCHEMBL12257987 | 0.68 | ADORA2B (0.53) | ADORA2BADORA3GLABLMADORA2A | |
| SCHEMBL27686732 | 0.68 | ADORA2B (0.54) | ADORA2BADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939197-A1 | 8-ethinylxanthine derivatives as selective A2A receptor antagonists | SCHWARZ PHARMA AG (DE) | 2008-07-02 | — | — | EP | disclosed |