Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | GBA1 | P04062 | 2/20 | 0.48 |
| ▸ | PNMT | P11086 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15701699 | 0.86 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11120749 | 0.81 | CYP1A2 (0.55) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2538061 | 0.80 | SIGMAR1 (0.58) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4871862 | 0.76 | GBA1 (0.48) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3874218 | 0.76 | SIGMAR1 (0.53) | CYP1A2CYP2C19CYP2D6CYP2C9SLC6A2 | |
| Hydrochloric Acid SCHEMBL31687522 | 0.74 | SIGMAR1 (0.51) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15701698 | 0.73 | SIGMAR1 (0.52) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4910869 | 0.72 | SIGMAR1 (0.51) | CYP1A2CYP2C19KCNH2GBA1PNMT | |
| SCHEMBL11456560 | 0.72 | SLC6A2 (0.44) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4760458 | 0.72 | SIGMAR1 (0.59) | CYP1A2CYP2C19CYP3A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287434-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-20 | — | — | US | disclosed |
| EP-1931620-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIQUIDS | Sanofi-Aventis (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007034252-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIQUIDS | SANOFI-AVENTIS (FR) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287434-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | CCR3, CCR1, CCR4 | CYP1A2 2460/4885CYP2C19 3078/4885CYP3A4 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.