Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.48 |
| ▸ | PNMT | P11086 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2538061 | 0.80 | SIGMAR1 (0.58) | GBA1PNMTTAAR1SIGMAR1CYP1A2 | |
| SCHEMBL4636336 | 0.76 | CYP1A2 (0.52) | GBA1PNMTTAAR1SIGMAR1CYP1A2 | |
| SCHEMBL4760458 | 0.72 | SIGMAR1 (0.59) | PNMTTAAR1SIGMAR1CYP1A2CYP2C19 | |
| SCHEMBL17788590 | 0.72 | PYCR1 (0.53) | PNMTTAAR1SIGMAR1CYP1A2CYP2C19 | |
| SCHEMBL18135502 | 0.70 | S1PR1 (0.35) | SIGMAR1CYP1A2CYP2C19SLC6A2SLC6A4 | |
| SCHEMBL25587803 | 0.70 | CYP1A2 (0.40) | GBA1SIGMAR1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL4037320 | 0.69 | PNMT (0.76) | PNMTTAAR1SIGMAR1CYP1A2CYP2C19 | |
| SCHEMBL9160104 | 0.68 | SIGMAR1 (0.67) | PNMTTAAR1SIGMAR1CYP1A2CYP2C19 | |
| SCHEMBL9640729 | 0.68 | CHRM2 (0.38) | MEN1ALDH1A1KMT2A | |
| SCHEMBL31497388 | 0.68 | PNMT (0.73) | PNMTTAAR1SIGMAR1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287434-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287434-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | CCR3, CCR1, CCR4 | GBA1 992/4885PNMT 3149/4885TAAR1 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.