Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 6/20 | 0.35 |
| ▸ | KCNK10 | P57789 | 4/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4636108 | 0.90 | RXFP1 (0.39) | RXFP1KCNK2KCNK10DHODHPPARG | |
| SCHEMBL4149970 | 0.90 | RXFP1 (0.35) | RXFP1KDM4EHPGDKCNK2KCNK10 | |
| SCHEMBL5316876 | 0.90 | RXFP1 (0.33) | RXFP1KCNK2KCNK10BRAF | |
| SCHEMBL4150571 | 0.80 | BRAF (0.33) | RXFP1KCNK2KCNK10BRAF | |
| SCHEMBL4145160 | 0.80 | RXFP1 (0.37) | RXFP1KCNK2KCNK10DHODHPPARG | |
| SCHEMBL5311662 | 0.80 | BRAF (0.33) | RXFP1KCNK2PPARGPPARDPPARA | |
| SCHEMBL5316114 | 0.77 | KMT2A (0.35) | RXFP1KCNK2KCNK10DHODHBRAF | |
| SCHEMBL4141961 | 0.76 | PPARG (0.37) | RXFP1KCNK2KCNK10PPARGPPARD | |
| SCHEMBL5313986 | 0.75 | HTT (0.36) | RXFP1KCNK2KCNK10PPARGPPARD | |
| SCHEMBL5335591 | 0.74 | HTT (0.34) | DHODHPPARGPPARDPPARASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |