Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314296 | 0.94 | ALDH1A1 (0.35) | HTTPPARGPPARDPPARABDKRB1 | |
| SCHEMBL5316854 | 0.88 | TLR7 (0.37) | RAB9ASMN1; SMN2POLBMAPTKMT2A | |
| SCHEMBL5316805 | 0.87 | MEN1 (0.34) | HTTPPARGPPARDPPARABDKRB1 | |
| SCHEMBL5315021 | 0.87 | HTT (0.37) | HTTRAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL5315879 | 0.86 | HTT (0.34) | HTTRAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL5318469 | 0.84 | SMN1; SMN2 (0.36) | HTTRAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL4149970 | 0.84 | RXFP1 (0.35) | HTTRAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL5316114 | 0.83 | KMT2A (0.35) | HTTMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL5316133 | 0.83 | POLB (0.39) | RAB9APOLBMEN1MAPTKMT2A | |
| SCHEMBL5314189 | 0.83 | TLR7 (0.37) | RAB9ASMN1; SMN2POLBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |