Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516381 | 0.74 | — | — | |
| SCHEMBL16050127 | 0.71 | PDPK1 (0.38) | PDPK1POLBMEN1KMT2AMAPT | |
| SCHEMBL2767832 | 0.68 | PDPK1 (0.45) | PDPK1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL12802320 | 0.66 | GABRA1 (0.40) | GABRA1GABRB2POLBMAPTSRD5A1 | |
| SCHEMBL9065044 | 0.66 | GABRA1 (0.40) | GABRA1GABRB2POLBMAPTSRD5A1 | |
| SCHEMBL44699 | 0.66 | GABRA1 (0.48) | GABRA1GABRB2POLBMEN1KMT2A | |
| SCHEMBL13995829 | 0.65 | CYP3A4 (0.40) | PDPK1MAPTGAAALDH1A1TDP1 | |
| SCHEMBL8055510 | 0.64 | ALDH1A1 (0.41) | GABRA1GABRB2MAPTALDH1A1 | |
| SCHEMBL472892 | 0.63 | KDM4E (0.54) | KMT2AMAPTHPGDGAAALDH1A1 | |
| SCHEMBL175607 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1543096-B1 | ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | CHEMTURA CORP (US) | 2008-04-30 | — | — | EP | disclosed |
| EP-1543096-A1 | ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | Uniroyal Chemical Company, Inc. (US) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004029183-A1 | ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2004-04-08 | — | — | WO | disclosed |
| US-6706671-B2 | A LUBRICANT, AND 4-ALKYL-1,2-DIHYDROPYRIDAZINE-3,6-DIONES, WHICH IS ASHLESS AND NONPHOSPHORUS CONTAINING ANTIWEAR, ANTIFATIGUE AND EXTREEM PRESSURE ADDITIVE | UNIROYAL CHEMICAL COMPANY, INC. | 2004-03-16 | — | — | US | disclosed |
| US-20030104953-A1 | A lubricant, and 4-alkyl-1,2-dihydropyridazine-3,6-diones, which is ashless and nonphosphorus containing antiwear, antifatigue and extreem pressure additive | UNIROYAL CHEMICAL COMPANY, INC. | 2003-06-05 | — | — | US | disclosed |