Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13648726 | 0.75 | L3MBTL3 (0.72) | SLC18A3GRIN2BMBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL11555679 | 0.75 | GRIN2B (0.42) | SLC18A3GRIN2BMBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL11560634 | 0.75 | SLC18A3 (0.52) | SLC18A3GRIN2BMBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL8584491 | 0.74 | L3MBTL3 (0.70) | SLC18A3GRIN2BMBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL22848097 | 0.74 | L3MBTL3 (0.70) | SLC18A3GRIN2BMBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL22848095 | 0.74 | L3MBTL3 (0.70) | SLC18A3GRIN2BMBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL2380225 | 0.74 | ALDH1A1 (0.43) | SLC18A3GRIN2BMBTD1L3MBTL3L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8814411 | 0.73 | L3MBTL3 (0.68) | SLC18A3GRIN2BMBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL1428236 | 0.72 | — | — | |
| SCHEMBL2176945 | 0.72 | L3MBTL3 (0.45) | SLC18A3GRIN2BMBTD1L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464641-B1 | 4-Phenyl-piperazinyl, -piperidinyl and tetrahydropyridyl derivatives as dopamine D4 antagonists | LUNDBECK & CO AS H (DK) | 2008-05-14 | — | — | EP | disclosed |
| EP-1464641-A1 | 4-Phenyl-piperazinyl, -piperidinyl and tetrahydropyridyl derivatives as dopamine D4 antagonists | H. Lundbeck A/S (DK) | 2004-10-06 | — | — | EP | disclosed |
| US-4148895-A | HYPOTENSIVE, ANTIARRHYMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |