Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 13/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637278 | 0.81 | ADORA2B (0.49) | ADORA2BADORA3ADORA2AMAOB | |
| SCHEMBL2541211 | 0.80 | ADORA2B (0.47) | ADORA2BADORA3ADORA2A | |
| SCHEMBL2547498 | 0.70 | ADORA2B (0.47) | ADORA2BADORA3ADORA2AADORA1 | |
| SCHEMBL4636557 | 0.69 | ADORA2B (0.46) | ADORA2BADORA3ADORA2AADORA1 | |
| SCHEMBL14142760 | 0.68 | ADORA2B (0.57) | ADORA2BADORA3ADORA2A | |
| SCHEMBL2542700 | 0.67 | ADORA1 (0.49) | ADORA2BADORA3ADORA2AMAOBADORA1 | |
| SCHEMBL4781188 | 0.67 | ADORA2B (0.45) | ADORA2BADORA3ADORA2AMAOBADORA1 | |
| SCHEMBL1954556 | 0.66 | ADORA2B (0.53) | ADORA2BADORA3ADORA2AMAOB | |
| SCHEMBL1954555 | 0.66 | ADORA2B (0.53) | ADORA2BADORA3ADORA2AMAOB | |
| SCHEMBL2535100 | 0.66 | ADORA2B (0.55) | ADORA2BADORA2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939197-A1 | 8-ethinylxanthine derivatives as selective A2A receptor antagonists | SCHWARZ PHARMA AG (DE) | 2008-07-02 | — | — | EP | disclosed |