SCHEMBL4637048

SCHEMBL4637048

Clc1cccnc1-c1[c][nH]cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2C P18825 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALOX15B O15296 1/20 0.35
NR1I2 O75469 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
HSP90AA1 P07900 1/20 0.35
CYP3A4 P08684 1/20 0.35
HTR1A P08908 1/20 0.35
ALOX5 P09917 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4637681 0.82 AXL (0.34) AXLPRKCI
SCHEMBL3623127 0.76 PRKCI (0.33) PRKCI
SCHEMBL5315498 0.74 ALDH1A1 (0.38) DPP4MEN1KMT2ATDP1ADRA2A
SCHEMBL2306238 0.73 DPP4 (0.48) DPP4MEN1KMT2ATDP1ADRA2A
SCHEMBL8688609 0.71 DPP4 (0.47) DPP4MEN1KMT2ATDP1ADRA2A
SCHEMBL4633189 0.71 DPP4 (0.47) DPP4MEN1KMT2ATDP1ADRA2A
SCHEMBL15636979 0.70 DPP4 (0.41) DPP4MEN1KMT2ATDP1KDM4E
SCHEMBL3628163 0.69 CYP2A6 (0.41) DPP4KMT2ATDP1KDM4EALDH1A1
SCHEMBL4986721 0.68 KDM4E (0.50) TDP1KDM4EALDH1A1LMNATP53
SCHEMBL1939367 0.68 AXL (0.34) DPP4CNR2S100A4CDC25BRPS6KA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed