SCHEMBL1939367

SCHEMBL1939367

Clc1cccnc1-c1[c][nH]cc1Br

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AXL P30530 1/20 0.34
DPP4 P27487 1/20 0.33
RPS6KA5 O75582 1/20 0.32
CNR2 P34972 1/20 0.32
CDC25B P30305 2/20 0.31
S100A4 P26447 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4777402 0.73 DPP4 (0.35) DPP4RPS6KA5CNR2CDC25BS100A4
SCHEMBL5314688 0.73 CYP2A6 (0.38) DPP4
SCHEMBL5313096 0.71 DPP4 (0.33) DPP4CNR2CDC25BS100A4
SCHEMBL2306238 0.70 DPP4 (0.48) DPP4CNR2CDC25BS100A4
SCHEMBL4637048 0.68 DPP4 (0.36) AXLDPP4RPS6KA5CNR2CDC25B
SCHEMBL5316789 0.68 TRPV1 (0.36) DPP4CNR2
SCHEMBL3633771 0.68 PTPN11 (0.36) DPP4RPS6KA5CNR2
SCHEMBL4633189 0.68 DPP4 (0.47) DPP4CNR2CDC25BS100A4
SCHEMBL8688609 0.68 DPP4 (0.47) DPP4CNR2CDC25BS100A4
SCHEMBL8716454 0.66 CYP1A2 (0.36) AXLDPP4RPS6KA5CNR2CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937664-B1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2011-06-15 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed