Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 9/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | CALML3 | P27482 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463748 | 0.90 | MAOA (0.53) | MAOACYP2E1F10TDO2CALML3 | |
| SCHEMBL463398 | 0.90 | MAOA (0.60) | MAOACYP2E1CALML3CYP2C9CYP2C19 | |
| SCHEMBL463586 | 0.87 | MAOA (0.48) | MAOACYP2E1F10ITGB3ITGA2B | |
| SCHEMBL463440 | 0.86 | MAOA (0.47) | MAOACYP2E1F10 | |
| SCHEMBL463337 | 0.85 | CYP2E1 (0.52) | MAOACYP2E1F10TDO2CALML3 | |
| SCHEMBL463342 | 0.84 | CYP2E1 (0.57) | MAOACYP2E1F10TDO2CALML3 | |
| SCHEMBL411619 | 0.83 | GRM2 (0.40) | TDO2CALML3 | |
| SCHEMBL412724 | 0.82 | CALML3 (0.50) | MAOATDO2CALML3CYP2C9CYP2C19 | |
| SCHEMBL463290 | 0.79 | MAOA (0.52) | MAOACYP2E1F10CALML3CYP2C9 | |
| SCHEMBL463449 | 0.79 | MAOA (0.51) | MAOACYP2E1F10CALML3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065170-A1 | Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | US | disclosed |
| WO-2012033952-A1 | 3 - PHENYL- 2 -OXO- 1, 3 -OXAZOLIDINES FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065170-A1 | Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections | NISCH, SI, VIP | MAOA 853/4885CYP2E1 352/4885F10 3187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.