Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637394 | 0.83 | DPP7 (0.55) | DPP7CYP1A2MAPK1CYP2C9HPGD | |
| SCHEMBL28321075 | 0.80 | DPP7 (0.52) | DPP7CYP1A2MAPK1CYP2C9HPGD | |
| SCHEMBL16151189 | 0.79 | DPP7 (0.39) | DPP7DPP4ANPEPERAP2 | |
| SCHEMBL7935848 | 0.76 | DPP7 (0.49) | DPP7MAPK1ALDH1A1SMN1; SMN2FDPS | |
| SCHEMBL4669860 | 0.76 | DPP7 (0.53) | DPP7CYP1A2MAPK1ALDH1A1DPP4 | |
| SCHEMBL5500053 | 0.74 | KDM4E (0.46) | DPP7CYP1A2MAPK1CYP2C9HPGD | |
| SCHEMBL28295367 | 0.74 | DPP7 (0.46) | DPP7CYP1A2MAPK1CYP2C9HPGD | |
| SCHEMBL8625882 | 0.74 | DPP7 (0.46) | DPP7CYP1A2MAPK1CYP2C9HPGD | |
| SCHEMBL499913 | 0.74 | KDM4E (0.46) | DPP7CYP1A2MAPK1CYP2C9HPGD | |
| SCHEMBL28340631 | 0.74 | DPP7 (0.70) | DPP7CYP1A2ALDH1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | claimed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | claimed |
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |