Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9774519 | 0.79 | ALDH1A1 (0.46) | MAPTMAPK1NPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL9774580 | 0.79 | ALDH1A1 (0.46) | MAPTMAPK1NPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL9774544 | 0.77 | MAPT (0.47) | MAPTMAPK1NPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL9621843 | 0.76 | SLC6A4 (0.44) | DPP7MAPTMAPK1NPSR1L3MBTL1 | |
| SCHEMBL2968888 | 0.76 | L3MBTL1 (0.54) | MAPTMAPK1NPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL4637130 | 0.76 | DPP7 (0.60) | DPP7MAPK1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL4637394 | 0.76 | DPP7 (0.55) | DPP7MAPTMAPK1NPSR1L3MBTL1 | |
| SCHEMBL500098 | 0.75 | ALDH1A1 (0.39) | DPP7MAPTMAPK1NPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28178646 | 0.75 | SLC6A4 (0.43) | MAPTMAPK1NPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL9621706 | 0.74 | SLC6A3 (0.46) | MAPTMAPK1NPSR1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306909-B1 | AMINOACID DERIVATIVES AND ESTERS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2001-10-23 | — | — | US | disclosed |