Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321075 | 0.98 | DPP7 (0.52) | DPP7L3MBTL1FDPSANPEPERAP2 | |
| SCHEMBL4637130 | 0.83 | DPP7 (0.60) | DPP7L3MBTL1FDPSANPEPERAP2 | |
| SCHEMBL28906618 | 0.77 | MAPT (0.45) | DPP7L3MBTL1FDPSMAPK1CYP1A2 | |
| SCHEMBL27834908 | 0.77 | L3MBTL1 (0.41) | DPP7L3MBTL1FDPSMAPK1CYP1A2 | |
| SCHEMBL7935848 | 0.76 | DPP7 (0.49) | DPP7L3MBTL1FDPSMAPK1MAPT | |
| SCHEMBL28325086 | 0.74 | SLC6A3 (0.47) | DPP7L3MBTL1FDPSMAPK1CYP1A2 | |
| SCHEMBL4411875 | 0.72 | DPP7 (0.44) | DPP7L3MBTL1MAPK1CYP1A2CYP2C9 | |
| SCHEMBL1428600 | 0.70 | DPP7 (0.45) | DPP7L3MBTL1FDPSANPEPERAP2 | |
| SCHEMBL28340631 | 0.69 | DPP7 (0.70) | DPP7CYP1A2ALDH1A1 | |
| SCHEMBL28343084 | 0.69 | DPP7 (0.70) | DPP7CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | claimed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | claimed |