Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.55 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719127 | 0.91 | SIGMAR1 (0.55) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| SCHEMBL2543003 | 0.86 | PYCR1 (0.58) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| SCHEMBL2830423 | 0.80 | SIGMAR1 (1.00) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| SCHEMBL5681292 | 0.80 | SIGMAR1 (1.00) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| Bromide SCHEMBL1780137 | 0.79 | SIGMAR1 (0.97) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| Bromide SCHEMBL31601130 | 0.79 | SIGMAR1 (0.97) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| SCHEMBL4719154 | 0.79 | SIGMAR1 (0.50) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| SCHEMBL14149704 | 0.78 | SIGMAR1 (0.71) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| SCHEMBL14846267 | 0.76 | IGF1R (0.53) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| SCHEMBL14376706 | 0.76 | CYP3A4 (0.77) | CYP1A2MEN1ALDH1A1MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931620-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIQUIDS | Sanofi-Aventis (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007034252-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIQUIDS | SANOFI-AVENTIS (FR) | 2007-03-29 | — | — | WO | disclosed |