Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3052861 | 0.92 | LPAR3 (0.45) | FAAHMEN1KMT2AEPHX2NOD1 | |
| SCHEMBL27949922 | 0.87 | EPHX2 (0.58) | FAAHMEN1KMT2AEPHX2NOD1 | |
| Hydrogen Sulfide SCHEMBL28113024 | 0.85 | EPHX2 (0.57) | FAAHMEN1KMT2AEPHX2NOD1 | |
| SCHEMBL21320215 | 0.85 | EPHX2 (0.53) | FAAHMEN1KMT2AEPHX2NOD1 | |
| SCHEMBL21724702 | 0.85 | LPAR3 (0.54) | EPHX2NOD1PLA2G2CLPAR3PLA2G10 | |
| SCHEMBL21724489 | 0.85 | LPAR3 (0.54) | EPHX2NOD1PLA2G2CLPAR3PLA2G10 | |
| SCHEMBL21724488 | 0.85 | LPAR3 (0.54) | EPHX2NOD1PLA2G2CLPAR3PLA2G10 | |
| SCHEMBL21724700 | 0.85 | LPAR3 (0.54) | EPHX2NOD1PLA2G2CLPAR3PLA2G10 | |
| SCHEMBL27104455 | 0.85 | LPAR3 (0.54) | EPHX2NOD1PLA2G2CLPAR3PLA2G10 | |
| SCHEMBL24095795 | 0.84 | FAAH (0.53) | FAAHMEN1KMT2AEPHX2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1938831-A1 | Novel exendin agonist compounds | Amylin Pharmaceuticals, Inc. (US) | 2008-07-02 | — | — | EP | disclosed |
| US-7157555-B1 | A polypeptide useful in the treatment of Type I and II diabetes; delaying and/or slowing gastric emptying; lowering plasma glucose levels | AMYLIN PHARMACEUTICALS, INC. (US) | 2007-01-02 | — | — | US | disclosed |
| EP-1019077-A4 | NOVEL EXENDIN AGONIST COMPOUNDS | AMYLIN PHARMACEUTICALS INC (US) | 2002-04-10 | — | — | EP | disclosed |
| EP-1019077-A1 | NOVEL EXENDIN AGONIST COMPOUNDS | AMYLIN PHARMACEUTICALS, INC. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999007404-A1 | NOVEL EXENDIN AGONIST COMPOUNDS | AMYLIN PHARMACEUTICALS, INC. (US) | 1999-02-18 | — | — | WO | disclosed |