Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860188 | 1.00 | KMT2A (0.58) | KMT2ASLC6A4ADRA2CCHRM2ADRA1A | |
| SCHEMBL7530583 | 0.85 | KMT2A (0.68) | KMT2ASLC6A4TSHRMEN1LMNA | |
| SCHEMBL27638557 | 0.82 | MMP8 (0.51) | KMT2ASLC6A4TSHRMEN1POLB | |
| SCHEMBL5861489 | 0.82 | MMP8 (0.51) | KMT2ASLC6A4TSHRMEN1POLB | |
| SCHEMBL9393822 | 0.82 | HTT (0.47) | KMT2AMEN1ALDH1A1CES2CES1 | |
| SCHEMBL13168073 | 0.81 | KMT2A (0.58) | KMT2ATSHRMEN1LMNAALDH1A1 | |
| SCHEMBL5789506 | 0.81 | KMT2A (0.62) | KMT2ASLC6A4ADRA2CCHRM2ADRA1A | |
| SCHEMBL6874324 | 0.81 | KMT2A (0.62) | KMT2ASLC6A4ADRA2CCHRM2ADRA1A | |
| SCHEMBL8571791 | 0.81 | KMT2A (0.62) | KMT2ASLC6A4ADRA2CCHRM2ADRA1A | |
| SCHEMBL11073226 | 0.79 | KMT2A (0.60) | KMT2ASLC6A4ADRA2CCHRM2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100400669-C | Stereoselective chemoenzymatic process for preparing optically enriched phenylglycidates | COUNCIL SCIENT IND RES (IN) | 2008-07-09 | — | — | CN | disclosed |
| EP-1601778-B1 | STEREOSELECTIVE CHEMOENZYMATIC PROCESS FOR PREPARING OPTICALLY ENRICHED PHENYLGLYCIDATES | COUNCIL SCIENT IND RES (IN) | 2008-07-02 | — | — | EP | disclosed |
| US-7060471-B2 | Stereoselective chemoenzymatic process for the preparation of optically enriched phenylglycidates as precursors of taxol side chain | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2006-06-13 | — | — | US | disclosed |
| CN-1759185-A | Stereoselective chemoenzymatic process for preparing optically enriched phenylglycidates | COUNCIL SCIENT IND RES (IN) | 2006-04-12 | — | — | CN | disclosed |
| EP-1601778-A1 | STEREOSELECTIVE CHEMOENZYMATIC PROCESS FOR PREPARING OPTICALLY ENRICHED PHENYLGLYCIDATES | Council of Scientific and Industrial Research (IN) | 2005-12-07 | — | — | EP | disclosed |
| US-20040259943-A1 | Stereoselective chemoenzymatic process for the preparation of optically enriched phenylglycidates as precursors of taxol side chain | COUNCIL OF SCIENTIFIC AND INDUSTRIAL (IN) | 2004-12-23 | — | — | US | disclosed |
| WO-2004081219-A1 | STEREOSELECTIVE CHEMOENZYMATIC PROCESS FOR PREPARING OPTICALLY ENRICHED PHENYLGLYCIDATES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259943-A1 | Stereoselective chemoenzymatic process for the preparation of optically enriched phenylglycidates as precursors of taxol side chain | GMDS, GPI, B3GAT3 | KMT2A 3273/4885SLC6A4 887/4885ADRA2C 625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.