Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27638557 | 1.00 | MMP8 (0.51) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL6579990 | 0.84 | MMP8 (0.53) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL9629339 | 0.83 | MMP8 (0.51) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL14130590 | 0.82 | MMP8 (0.54) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL4637554 | 0.82 | KMT2A (0.58) | MEN1KMT2AMAPTTSHRPOLB | |
| SCHEMBL23342965 | 0.82 | MMP8 (0.54) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL606117 | 0.82 | MMP8 (0.54) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL5860188 | 0.82 | KMT2A (0.58) | MEN1KMT2AMAPTTSHRPOLB | |
| SCHEMBL9126861 | 0.82 | MMP8 (0.54) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL11938487 | 0.82 | MMP8 (0.54) | MMP8PIN1MEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060471-B2 | Stereoselective chemoenzymatic process for the preparation of optically enriched phenylglycidates as precursors of taxol side chain | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2006-06-13 | — | — | US | disclosed |