SCHEMBL4637758

SCHEMBL4637758

C=CC(=O)NS(=O)(=O)c1ccccc1.C=CC(=O)Nc1ccccc1S(N)(=O)=O

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 17/20 0.48
CA2 P00918 17/20 0.48
CA9 Q16790 3/20 0.47
PTGES2 Q9H7Z7 2/20 0.43
CA4 P22748 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29733701 0.88 CA1 (0.59) CA1CA2CA9
SCHEMBL964767 0.88 CA1 (0.59) CA1CA2CA9
SCHEMBL962549 0.82 CA2 (0.55) CA1CA2
SCHEMBL13921975 0.77 TGM2 (0.45) CA1CA2CA9
SCHEMBL9568726 0.76 SMN1; SMN2 (0.52)
SCHEMBL3813620 0.75 TGM2 (0.47) CA1CA2
SCHEMBL29588334 0.74 TGM2 (0.50) CA1CA2
SCHEMBL1813156 0.74 TGM2 (0.50) CA1CA2
SCHEMBL3820006 0.74 TGM2 (0.56)
SCHEMBL5175046 0.74 KDM4E (0.61) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1541644-B1 Ink composition and inkjet recording method FUJIFILM CORP (JP) 2008-07-02 EP disclosed