Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639457 | 0.86 | USP2 (0.35) | USP2CYP3A4CYP2D6TSHRTACR1 | |
| SCHEMBL4637768 | 0.84 | USP2 (0.37) | USP2CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL4638914 | 0.83 | ALDH1A1 (0.43) | TSHRTACR1MAPT | |
| SCHEMBL4708145 | 0.83 | AKR1C3 (0.36) | USP2MEN1KMT2ACYP2D6TSHR | |
| SCHEMBL4638494 | 0.79 | USP2 (0.42) | USP2CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL4637963 | 0.79 | USP2 (0.45) | USP2CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL4639425 | 0.78 | USP2 (0.35) | USP2CYP3A4CYP2D6TSHRTACR1 | |
| SCHEMBL4637887 | 0.76 | USP2 (0.36) | USP2CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL4637960 | 0.76 | USP2 (0.41) | USP2CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL4638484 | 0.74 | AKR1C3 (0.35) | USP2MEN1KMT2ACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501808-B1 | TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-07-02 | — | — | EP | disclosed |