Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 14/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280631 | 0.94 | MTNR1B (0.40) | MTNR1BF10MTNR1A | |
| SCHEMBL5278811 | 0.94 | MTNR1B (0.40) | MTNR1BF10MTNR1A | |
| SCHEMBL4638364 | 0.92 | SLC6A9 (0.36) | MTNR1BMTNR1AITGB2ICAM1ITGAL | |
| SCHEMBL5295500 | 0.86 | MTNR1B (0.39) | MTNR1BMTNR1A | |
| SCHEMBL4639209 | 0.81 | MTNR1B (0.41) | MTNR1BMTNR1A | |
| SCHEMBL4638198 | 0.81 | DPP4 (0.36) | KDM4CF10 | |
| SCHEMBL4638122 | 0.79 | SCN9A (0.31) | MTNR1B | |
| SCHEMBL5242847 | 0.79 | MTNR1B (0.38) | MTNR1BMTNR1A | |
| SCHEMBL4637760 | 0.79 | SLC18A2 (0.36) | MTNR1BKDM4CF10 | |
| SCHEMBL5241375 | 0.78 | MTNR1B (0.39) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951712-A2 | CHEMICAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007059952-A2 | 1-BENZAZEPINE-3-SULFONYLAMINO-2-PYRRLORIDONES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-05-31 | — | — | WO | disclosed |