Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14165580 | 0.85 | ALOX5 (0.46) | ALOX5SKP2HTR2ASLC2A1ALDH1A1 | |
| SCHEMBL1170745 | 0.80 | SKP2 (0.41) | SKP2HTR2ATLR8GCGR | |
| SCHEMBL8014993 | 0.76 | PPARA (0.41) | ALOX5ALDH1A1MAPT | |
| SCHEMBL28104171 | 0.74 | ALOX5 (0.42) | ALOX5SKP2HTR2ASLC2A1ALDH1A1 | |
| SCHEMBL24180080 | 0.73 | HMGCR (0.37) | ALOX5HTR2AALDH1A1 | |
| SCHEMBL45792 | 0.72 | SKP2 (0.50) | SKP2HTR2ATLR8ALDH1A1MAPT | |
| SCHEMBL3883594 | 0.72 | ALDH1A1 (0.37) | ALOX5ALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL23829848 | 0.70 | ALDH1A1 (0.37) | ALDH1A1MAPTTHRBTDP1PTGS2 | |
| SCHEMBL9516123 | 0.70 | SKP2 (0.48) | SKP2HTR2ATLR8ALDH1A1MAPT | |
| SCHEMBL294503 | 0.70 | SKP2 (0.48) | SKP2HTR2ATLR8ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888063-A1 | ANTIFUNGAL AGENTS | F2G Ltd. (GB) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006123145-A1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2006-11-23 | — | — | WO | disclosed |