Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14315826 | 1.00 | FKBP1A (0.46) | FKBP1AMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL26723979 | 1.00 | FKBP1A (0.46) | FKBP1AMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL1911483 | 0.95 | FKBP1A (0.51) | FKBP1AMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL19215660 | 0.85 | RAB9A (0.54) | MAPTALDH1A1RAB9AKDM4ETSHR | |
| SCHEMBL19737744 | 0.85 | RAB9A (0.54) | MAPTALDH1A1RAB9AKDM4ETSHR | |
| SCHEMBL278662 | 0.81 | TSHR (0.46) | FKBP1ARAB9ATSHRSMN1; SMN2 | |
| SCHEMBL1684095 | 0.81 | TSHR (0.46) | FKBP1ARAB9ATSHRSMN1; SMN2 | |
| SCHEMBL13910188 | 0.81 | TSHR (0.46) | FKBP1ARAB9ATSHRSMN1; SMN2 | |
| SCHEMBL17244892 | 0.80 | RAB9A (0.35) | FKBP1AMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL12767122 | 0.80 | MAPT (0.40) | MAPTALDH1A1RAB9AKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937663-A1 | THIOPHENE DERIVATIVES AS PPAR AGONISTS I | Inpharmatica Limited (GB) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007036730-A1 | THIOPHENE DERIVATIVES AS PPAR AGONISTS I | INPHARMATICA LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |