SCHEMBL4638546

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7895808	0.84	LMNA (0.47)	MAPTLMNAPPARGNCOA2NCOA1
	SCHEMBL3131211	0.79	F2 (0.50)	F2LMNAPPARGNCOA2NCOA1
	SCHEMBL8871784	0.77	F2 (0.52)	F2LMNAPPARGNCOA2NCOA1
	SCHEMBL28780755	0.76	F2 (0.47)	F2MAPTLMNAPPARGNCOA2
	SCHEMBL22638709	0.76	HDAC4 (0.50)	MAPTLMNAPPARGNCOA2NCOA1
	SCHEMBL4638550	0.73	MAPT (0.47)	MAPTLMNALOXKMT2AMEN1
	SCHEMBL29512717	0.73	MAPT (0.47)	MAPTLOX
	SCHEMBL22588716	0.71	GAA (0.52)	F2MAPTLMNAPPARGNCOA2
	SCHEMBL16068076	0.71	MAPT (0.49)	MAPTLMNANPSR1LOXKMT2A
	SCHEMBL6181512	0.71	F2 (0.71)	F2MAPTNPSR1IKBKBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.