Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049156 | 0.90 | MAPT (0.40) | PIM1TP53MAPTLMNACYP1A2 | |
| SCHEMBL6688204 | 0.71 | MAPT (0.45) | PIM1TP53MAPTLMNACYP1A2 | |
| SCHEMBL7702135 | 0.70 | PIM1 (0.39) | PIM1TP53MAPTLMNACYP1A2 | |
| SCHEMBL8040477 | 0.68 | MAPT (0.42) | PIM1TP53MAPTLMNACYP1A2 | |
| SCHEMBL5094564 | 0.65 | MAPT (0.39) | PIM1TP53MAPTLMNACYP1A2 | |
| SCHEMBL731490 | 0.63 | PIM1 (0.33) | PIM1 | |
| SCHEMBL30426195 | 0.62 | — | — | |
| SCHEMBL3274379 | 0.62 | MAPT (0.42) | TP53MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL5969253 | 0.61 | MAPT (0.41) | TP53MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL8794463 | 0.60 | MAPT (0.40) | TP53MAPTLMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465019-B1 | Imaging members | XEROX CORP (US) | 2008-08-06 | — | — | EP | claimed |
| US-7297458-B2 | Electrophotographic image receivers comprising flexible supporting substrates having electroconductive, charge control, generating, transfer multilayers, binders and optionally adhesives; photoreceptors | XEROX CORPORATION (US) | 2007-11-20 | — | — | US | claimed |
| US-7163771-B2 | Imaging members | XEROX CORPORATION (US) | 2007-01-16 | — | — | US | claimed |
| US-20050287453-A1 | A photoconductive imaging member containing a supporting substrate, and a single layer comprised of a photogenerator component, a charge transport component, an electron transport component (alkylalcohol derivative) , and a polymer binder. | XEROX CORPORATION | 2005-12-29 | — | — | US | claimed |
| US-20050287454-A1 | Electrophotographic image receivers comprising flexible supporting substrates having electroconductive, charge control, generating, transfer multilayers, binders and optionally adhesives; photoreceptors | XEROX CORPORATION | 2005-12-29 | — | — | US | claimed |
| US-20040197685-A1 | Imaging members | XEROX CORPORATION | 2004-10-07 | — | — | US | claimed |
| EP-1465019-A2 | Imaging members | Xerox Corporation (US) | 2004-10-06 | — | — | EP | claimed |
| EP-1465019-B1 | Imaging members | XEROX CORP (US) | 2008-08-06 | — | — | EP | disclosed |
| US-7297458-B2 | Electrophotographic image receivers comprising flexible supporting substrates having electroconductive, charge control, generating, transfer multilayers, binders and optionally adhesives; photoreceptors | XEROX CORPORATION (US) | 2007-11-20 | — | — | US | disclosed |
| US-7223507-B2 | Imaging members | XEROX CORPORATION (US) | 2007-05-29 | — | — | US | disclosed |
| US-7163771-B2 | Imaging members | XEROX CORPORATION (US) | 2007-01-16 | — | — | US | disclosed |
| US-20050287453-A1 | A photoconductive imaging member containing a supporting substrate, and a single layer comprised of a photogenerator component, a charge transport component, an electron transport component (alkylalcohol derivative) , and a polymer binder. | XEROX CORPORATION | 2005-12-29 | — | — | US | disclosed |
| US-20050287454-A1 | Electrophotographic image receivers comprising flexible supporting substrates having electroconductive, charge control, generating, transfer multilayers, binders and optionally adhesives; photoreceptors | XEROX CORPORATION | 2005-12-29 | — | — | US | disclosed |
| JP-2004310089-A | PHOTOCONDUCTIVE IMAGE FORMING MEMBER | XEROX CORP | 2004-11-04 | — | — | JP | disclosed |
| US-20040197685-A1 | Imaging members | XEROX CORPORATION | 2004-10-07 | — | — | US | disclosed |
| EP-1465019-A2 | Imaging members | Xerox Corporation (US) | 2004-10-06 | — | — | EP | disclosed |