SCHEMBL731490

SCHEMBL731490

N#CC(C#N)=C1c2ccccc2C2=CC=CC(=O)C21

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7702135 0.78 PIM1 (0.39) PIM1
SCHEMBL6688204 0.75 MAPT (0.45) PIM1
SCHEMBL21938552 0.70 PIM1 (0.38) PIM1
SCHEMBL7102551 0.70 MAPT (0.42) PIM1
SCHEMBL8746334 0.68 KMT2A (0.35)
SCHEMBL23501565 0.66 PIM1 (0.46) PIM1
SCHEMBL13324474 0.66 PIM1 (0.50) PIM1
SCHEMBL28213822 0.66 PIM1 (0.46) PIM1
SCHEMBL14067580 0.66 PIM1 (0.50) PIM1
SCHEMBL30777519 0.66 PIM1 (0.46) PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142647-B2 For making ultra low sulfur fuels; adsorbent which is silica functionalized with 2,4,5,7-tetranitro-9-fluorenylideneaminooxy propionic acid is contacted with aromatic compound, a dibenzothiophene compound, and an aliphatic solvent; regenerating the adsorbent with toluene CHEVRON U.S.A. INC. (US) 2012-03-27 US disclosed
US-8138369-B2 Removal of branched dibenzothiophenes from hydrocarbon mixtures via charge transfer complexes with a TAPA-functionalized adsorbent CHEVRON U.S.A. INC. (US) 2012-03-20 US disclosed
WO-2010074894-A2 ADSORPTION OF DIBENZOTHIOPHENES FROM HYDROCARBON AND MODEL DIESEL FEEDS CHEVRON U.S.A. INC. (US) 2010-07-01 WO disclosed
US-20100147748-A1 ADSORPTION OF DIBENZOTHIOPHENES FROM HYDROCARBON AND MODEL DIESEL FEEDS CHEVRON U.S.A. INC. 2010-06-17 US disclosed
US-20090076221-A1 REMOVAL OF BRANCHED DIBENZOTHIOPHENES FROM HYDROCARBON MIXTURES VIA CHARGE TRANSFER COMPLEXES WITH A TAPA-FUNCTIONALIZED ADSORBENT CHEVRON U.S.A. INC. 2009-03-19 US disclosed
WO-2008154331-A1 REMOVAL OF BRANCHED DIBENZOTHIOPHENES FROM HYDROCARBON MIXTURES VIA CHARGE TRANSFER COMPLEXES WITH A TAPA-FUNCTIONALIZED ADSORBENT CHEVRON U.S.A. INC. (US) 2008-12-18 WO disclosed
EP-0534514-B1 Electrophotographic recording material AGFA GEVAERT NV (BE) 1996-11-20 EP disclosed
EP-0462327-B1 Electrophotographic recording material AGFA GEVAERT NV (BE) 1995-09-27 EP disclosed
EP-0428214-B1 Electrophotographic recording material AGFA GEVAERT NV (BE) 1995-03-29 EP disclosed
EP-0388531-B1 Recording material suited for use in electrophotography AGFA GEVAERT NV (BE) 1994-10-26 EP disclosed
US-4990421-A High charge generating compound from diazonium salt and aromatic hydroxyamide or imide coupler AGFA-GEVAERT, N.V. (BE) 1991-02-05 US disclosed
US-4981768-A Photosensitive recording material having an N-aryl carbazole p-type charge transport compound AGFA-GEVAERT, N.V. (BE) 1991-01-01 US disclosed
EP-0388531-A1 Recording material suited for use in electrophotography AGFA-GEVAERT N.V. (BE) 1990-09-26 EP disclosed
US-4943502-A TWO LAYER SYSTEM OF CHARGE GENERATING AND CHARGE TRANSPORTING COMPOUNDS AGFA-GEVAERT, N.V. (BE) 1990-07-24 US disclosed
US-4923774-A Layered electrophotographic recording element comprising p-type charge transport compounds AGFA-GEVAERT, N.V. (BE) 1990-05-08 US disclosed
EP-0350984-A1 Electrophotographic recording material containing a trisazo dye AGFA-GEVAERT N.V. (BE) 1990-01-17 EP disclosed
EP-0349034-A1 Electrophotographic recording material AGFA-GEVAERT N.V. (BE) 1990-01-03 EP disclosed
EP-0347960-A1 Photosensitive recording material suited for use in electrophotography AGFA-GEVAERT N.V. (BE) 1989-12-27 EP disclosed
EP-0347967-A1 Photosensitive recording material suited for use in electrophotography AGFA-GEVAERT N.V. (BE) 1989-12-27 EP disclosed
EP-0034497-B1 ELECTROPHOTOGRAPHIC LIGHT-SENSITIVE MEDIA Canon Inc. (JP) 1985-09-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090076221-A1 REMOVAL OF BRANCHED DIBENZOTHIOPHENES FROM HYDROCARBON MIXTURES VIA CHARGE TRANSFER COMPLEXES WITH A TAPA-FUNCTIONALIZED ADSORBENT TST, SLC43A1, BCAT1 PIM1 2341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.