SCHEMBL4639100

SCHEMBL4639100

O=C(O)C1(c2ccccc2)CCCCC1(C(=O)O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.63
HDAC4 P56524 2/20 0.50
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
LMNA P02545 2/20 0.44
HTT P42858 2/20 0.44
HSD11B1 P28845 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4639318 0.95 AKR1C1 (0.57) AKR1C1HDAC4MEN1KMT2ANPSR1
SCHEMBL4639359 0.91 AKR1C1 (0.56) AKR1C1HDAC4MEN1KMT2ALMNA
SCHEMBL20242049 0.84 AKR1C1 (0.55) AKR1C1HDAC4MEN1KMT2ANPSR1
SCHEMBL20241840 0.84 AKR1C1 (0.55) AKR1C1HDAC4MEN1KMT2ANPSR1
SCHEMBL20241661 0.84 AKR1C1 (0.55) AKR1C1HDAC4MEN1KMT2ANPSR1
SCHEMBL28426673 0.83 AKR1C1 (0.53) AKR1C1HDAC4MEN1KMT2ANPSR1
SCHEMBL7602755 0.81 AKR1C1 (0.50) AKR1C1HDAC4MEN1KMT2ANPSR1
SCHEMBL20241978 0.79 AKR1C1 (0.50) AKR1C1HDAC4MEN1KMT2ANPSR1
SCHEMBL5129613 0.77 AKR1C1 (0.47) AKR1C1HDAC4MEN1KMT2ANPSR1
SCHEMBL65167 0.77 AKR1C1 (1.00) AKR1C1HDAC4MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1156071-B2 A method for manufacturing polycarbonate GEN ELECTRIC (US) 2008-08-06 EP disclosed
EP-1156071-B1 A method for manufacturing polycarbonate GEN ELECTRIC (US) 2004-08-04 EP disclosed
US-6482877-B2 MELT PROCESSABILITY; MIXTURE WITH PHOSPHOROUS ACID, SULFUR COMPOUND AND FATTY ESTER GENERAL ELECTRIC COMPANY 2002-11-19 US disclosed
US-6455667-B1 FILTERING A POLYCARBONATE MELT THROUGH A PASSIVATION TREATED METAL FILTER; NONCONTAMINATION GENERAL ELECTRIC COMPANY 2002-09-24 US disclosed
EP-1156071-A1 A method for manufacturing polycarbonate GENERAL ELECTRIC COMPANY (US) 2001-11-21 EP disclosed
EP-1156078-A1 Polycarbonate resin composition for optical use GENERAL ELECTRIC COMPANY (US) 2001-11-21 EP disclosed
US-20010041759-A1 Polycarbonate resin composition for optical use SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2001-11-15 US disclosed
US-6271290-B1 OPTICAL POLYMERS PREPARED BY MELT CONDENSATION GENERAL ELECTRIC COMPANY 2001-08-07 US disclosed
US-5514767-A Hot-melt polycondensation method for manufacturing a polycarbonate composition GENERAL ELECTRIC COMPANY (US) 1996-05-07 US disclosed