Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5129613 | 0.86 | AKR1C1 (0.47) | AKR1C1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4639359 | 0.85 | AKR1C1 (0.56) | AKR1C1MEN1KMT2AHTTCYP2C9 | |
| SCHEMBL11444396 | 0.84 | MEN1 (0.62) | AKR1C1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL19469690 | 0.84 | ELOVL1 (0.47) | AKR1C1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4639318 | 0.81 | AKR1C1 (0.57) | AKR1C1MEN1KMT2ANPSR1HTT | |
| SCHEMBL4639100 | 0.81 | AKR1C1 (0.63) | AKR1C1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL20241840 | 0.79 | AKR1C1 (0.55) | AKR1C1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL20241978 | 0.79 | AKR1C1 (0.50) | AKR1C1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL20241661 | 0.79 | AKR1C1 (0.55) | AKR1C1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL20242049 | 0.79 | AKR1C1 (0.55) | AKR1C1MEN1KMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482877-B2 | MELT PROCESSABILITY; MIXTURE WITH PHOSPHOROUS ACID, SULFUR COMPOUND AND FATTY ESTER | GENERAL ELECTRIC COMPANY | 2002-11-19 | — | — | US | disclosed |
| EP-1156078-A1 | Polycarbonate resin composition for optical use | GENERAL ELECTRIC COMPANY (US) | 2001-11-21 | — | — | EP | disclosed |
| US-20010041759-A1 | Polycarbonate resin composition for optical use | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2001-11-15 | — | — | US | disclosed |
| US-6271290-B1 | OPTICAL POLYMERS PREPARED BY MELT CONDENSATION | GENERAL ELECTRIC COMPANY | 2001-08-07 | — | — | US | disclosed |