SCHEMBL4639359

SCHEMBL4639359

O=C(O)C1(c2ccccc2)CCC1(C(=O)O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.56
KMT2A Q03164 5/20 0.44
MEN1 O00255 3/20 0.44
HDAC4 P56524 3/20 0.44
HSD11B1 P28845 2/20 0.42
OPRM1 P35372 1/20 0.42
OPRL1 P41146 1/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
CYP2C9 P11712 1/20 0.41
TET3 O43151 1/20 0.41
FBXL19 Q6PCT2 1/20 0.41
CXXC5 Q7LFL8 1/20 0.41
TET1 Q8NFU7 1/20 0.41
KDM2B Q8NHM5 1/20 0.41
CXXC4 Q9H2H0 1/20 0.41
KDM2A Q9Y2K7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4639100 0.91 AKR1C1 (0.63) AKR1C1KMT2AMEN1HDAC4HSD11B1
SCHEMBL4639318 0.91 AKR1C1 (0.57) AKR1C1KMT2AMEN1HDAC4HSD11B1
SCHEMBL7602755 0.85 AKR1C1 (0.50) AKR1C1KMT2AMEN1HDAC4LMNA
SCHEMBL5129613 0.81 AKR1C1 (0.47) AKR1C1KMT2AMEN1HDAC4LMNA
SCHEMBL19469690 0.79 ELOVL1 (0.47) AKR1C1KMT2AMEN1LMNAHTT
SCHEMBL11444396 0.79 MEN1 (0.62) AKR1C1KMT2AMEN1HDAC4LMNA
SCHEMBL20241661 0.79 AKR1C1 (0.55) AKR1C1KMT2AMEN1HDAC4HSD11B1
SCHEMBL20241840 0.79 AKR1C1 (0.55) AKR1C1KMT2AMEN1HDAC4HSD11B1
SCHEMBL20241978 0.79 AKR1C1 (0.50) AKR1C1KMT2AMEN1HDAC4HSD11B1
SCHEMBL20242049 0.79 AKR1C1 (0.55) AKR1C1KMT2AMEN1HDAC4HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1156071-B2 A method for manufacturing polycarbonate GEN ELECTRIC (US) 2008-08-06 EP disclosed
EP-1156071-B1 A method for manufacturing polycarbonate GEN ELECTRIC (US) 2004-08-04 EP disclosed
US-6482877-B2 MELT PROCESSABILITY; MIXTURE WITH PHOSPHOROUS ACID, SULFUR COMPOUND AND FATTY ESTER GENERAL ELECTRIC COMPANY 2002-11-19 US disclosed
US-6455667-B1 FILTERING A POLYCARBONATE MELT THROUGH A PASSIVATION TREATED METAL FILTER; NONCONTAMINATION GENERAL ELECTRIC COMPANY 2002-09-24 US disclosed
EP-1156071-A1 A method for manufacturing polycarbonate GENERAL ELECTRIC COMPANY (US) 2001-11-21 EP disclosed
EP-1156078-A1 Polycarbonate resin composition for optical use GENERAL ELECTRIC COMPANY (US) 2001-11-21 EP disclosed
US-20010041759-A1 Polycarbonate resin composition for optical use SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2001-11-15 US disclosed
US-6271290-B1 OPTICAL POLYMERS PREPARED BY MELT CONDENSATION GENERAL ELECTRIC COMPANY 2001-08-07 US disclosed
US-5514767-A Hot-melt polycondensation method for manufacturing a polycarbonate composition GENERAL ELECTRIC COMPANY (US) 1996-05-07 US disclosed