Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | CETP | P11597 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639106 | 1.00 | ALDH1A1 (0.34) | ALDH1A1CETPLPAR1LPAR5KDM4E | |
| SCHEMBL7370771 | 0.82 | PTGER4 (0.43) | ALDH1A1MEN1KMT2ATHRBNPC1 | |
| SCHEMBL7370769 | 0.82 | PTGER4 (0.43) | ALDH1A1MEN1KMT2ATHRBNPC1 | |
| SCHEMBL6418148 | 0.81 | LY96 (0.38) | ALDH1A1CETPMEN1KMT2A | |
| SCHEMBL6418150 | 0.81 | LY96 (0.38) | ALDH1A1CETPMEN1KMT2A | |
| SCHEMBL6418121 | 0.80 | POLB (0.49) | ALDH1A1LPAR1KDM4EHSD17B10HPGD | |
| SCHEMBL6418683 | 0.79 | SSTR4 (0.39) | ALDH1A1CETPLPAR1LPAR5HSD17B10 | |
| SCHEMBL6422006 | 0.79 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL6422010 | 0.79 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL6420626 | 0.77 | POLB (0.38) | ALDH1A1CETPHSD17B10TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628949-A4 | PROCESS AND INTERMEDIATES FOR PREPARING BENZAZEPINES | SMITHKLINE BEECHAM CORP (US) | 2008-07-02 | — | — | EP | disclosed |
| US-7368566-B2 | Process and intermediates for preparing benzazepines | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-06 | — | — | US | disclosed |
| US-20060194786-A1 | Process and intermediates for preparing benzazepines | SMITHKLINE BEECHAM CORPORATION | 2006-08-31 | — | — | US | disclosed |
| EP-1628949-A2 | PROCESS AND INTERMEDIATES FOR PREPARING BENZAZEPINES | SMITHKLINE BEECHAM CORPORATION (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004089890-A2 | PROCESS AND INTERMEDIATES FOR PREPARING BENZAZEPINES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194786-A1 | Process and intermediates for preparing benzazepines | CYP2E1, CYP1B1, CYP3A4 | ALDH1A1 279/4885CETP 2057/4885LPAR1 2200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.