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Sulfamide

Sulfamide

SCHEMBL4639261

Cc1ccc(-c2nc(C(F)(F)F)cn2-c2ccccc2)cc1Cl.NS(N)(=O)=O

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 20/20 0.80
▸ PTGS1 P23219 14/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL212940 0.89 PTGS2 (1.00) PTGS2PTGS1
Sulfamide SCHEMBL4638345 0.87 PTGS2 (0.81) PTGS2PTGS1
SCHEMBL3250262 0.85 PTGS2 (1.00) PTGS2PTGS1
Sulfamide SCHEMBL4638211 0.84 PTGS2 (0.81) PTGS2PTGS1
SCHEMBL8025612 0.84 PTGS2 (0.69) PTGS2PTGS1
SCHEMBL8297503 0.84 PTGS2 (0.76) PTGS2PTGS1
Sulfamide SCHEMBL4639682 0.84 PTGS2 (0.80) PTGS2PTGS1
Sulfamide SCHEMBL4639731 0.83 PTGS2 (0.82) PTGS2PTGS1
SCHEMBL5594591 0.82 PTGS2 (0.88) PTGS2PTGS1
SCHEMBL6265435 0.81 PTGS2 (0.73) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1479385-B1 Use of cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia SEARLE LLC (US) 2008-07-02 — — EP claimed