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Sugi Predict / Compounds / Sulfamide

Sulfamide

Sulfamide

SCHEMBL4639682

Cc1cccc(-c2nc(C(F)(F)F)cn2-c2ccccc2)c1.NS(N)(=O)=O

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 20/20 0.80
▸ PTGS1 P23219 9/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfamide SCHEMBL4639731 0.90 PTGS2 (0.82) PTGS2PTGS1
SCHEMBL214166 0.89 PTGS2 (1.00) PTGS2PTGS1
Sulfamide SCHEMBL4638211 0.88 PTGS2 (0.81) PTGS2PTGS1
Sulfamide SCHEMBL4638353 0.87 PTGS2 (0.80) PTGS2PTGS1
Sulfamide SCHEMBL4638575 0.87 PTGS2 (0.80) PTGS2PTGS1
SCHEMBL214198 0.85 PTGS2 (1.00) PTGS2PTGS1
Sulfamide SCHEMBL4639261 0.84 PTGS2 (0.80) PTGS2PTGS1
Sulfamide SCHEMBL4638289 0.83 PTGS2 (0.79) PTGS2PTGS1
SCHEMBL8028157 0.81 PTGS2 (0.77) PTGS2PTGS1
SCHEMBL13437655 0.81 PTGS2 (0.72) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1479385-B1 Use of cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia SEARLE LLC (US) 2008-07-02 — — EP claimed