Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.73 |
| ▸ | CA1 | P00915 | 1/20 | 0.73 |
| ▸ | CA2 | P00918 | 1/20 | 0.73 |
| ▸ | CA9 | Q16790 | 1/20 | 0.73 |
| ▸ | SENP7 | Q9BQF6 | 8/20 | 0.69 |
| ▸ | GAA | P10253 | 10/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | MEN1 | O00255 | 8/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 6/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 6/20 | 0.67 |
| ▸ | CASP3 | P42574 | 4/20 | 0.67 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.67 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.67 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639506 | 1.00 | CA12 (0.73) | CA12CA1CA2CA9SENP7 | |
| SCHEMBL27139059 | 0.82 | SENP7 (1.00) | SENP7GAAMAPTMEN1KMT2A | |
| SCHEMBL24629300 | 0.82 | SENP7 (1.00) | SENP7GAAMAPTMEN1KMT2A | |
| SCHEMBL24629299 | 0.80 | SENP7 (1.00) | SENP7GAAMAPTMEN1KMT2A | |
| SCHEMBL27126553 | 0.80 | SENP7 (1.00) | SENP7GAAMAPTMEN1KMT2A | |
| SCHEMBL27123871 | 0.80 | MEN1 (1.00) | SENP7GAAMAPTMEN1KMT2A | |
| SCHEMBL26983136 | 0.80 | MEN1 (1.00) | SENP7GAAMAPTMEN1KMT2A | |
| SCHEMBL24629301 | 0.79 | SENP7 (1.00) | SENP7GAAMAPTMEN1KMT2A | |
| SCHEMBL27127002 | 0.79 | SENP7 (1.00) | SENP7GAAMAPTMEN1KMT2A | |
| SCHEMBL24629292 | 0.73 | GAA (0.75) | CA12CA1CA2CA9SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476149-B1 | SUBSTITUTED HYDRAZONES AS INHIBITORS OF CYCLOOXYGENASE-2 | UNIV TEMPLE (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1476149-A4 | SUBSTITUTED HYDRAZONES AS INHIBITORS OF CYCLOOXYGENASE-2 | UNIV TEMPLE (US) | 2005-09-14 | — | — | EP | disclosed |
| EP-1476149-A2 | SUBSTITUTED HYDRAZONES AS INHIBITORS OF CYCLOOXYGENASE-2 | Temple University of the Commonwealth System of Higher Education (US) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003049698-A2 | SUBSTITUTED HYDRAZONES AS INHIBITORS OF CYCLOOXYGENASE-2 | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2003-06-19 | — | — | WO | disclosed |