Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.75 |
| ▸ | MAPT | P10636 | 8/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.75 |
| ▸ | ATM | Q13315 | 1/20 | 0.75 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 7/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 5/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 5/20 | 0.64 |
| ▸ | CASP3 | P42574 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27135266 | 1.00 | GAA (0.75) | GAAMAPTTDP1ATMRECQL | |
| SCHEMBL24629300 | 0.80 | SENP7 (1.00) | GAAMAPTTDP1ATMRECQL | |
| SCHEMBL27139059 | 0.80 | SENP7 (1.00) | GAAMAPTTDP1ATMRECQL | |
| SCHEMBL2522175 | 0.79 | GAA (0.64) | GAAMAPTTDP1ATMRECQL | |
| SCHEMBL2521031 | 0.79 | GAA (0.64) | GAAMAPTTDP1ATMRECQL | |
| SCHEMBL30899178 | 0.79 | MAPT (0.56) | GAAMAPTTDP1ATMRECQL | |
| SCHEMBL30899179 | 0.79 | MAPT (0.56) | GAAMAPTTDP1ATMRECQL | |
| SCHEMBL27126553 | 0.78 | SENP7 (1.00) | GAAMAPTTDP1ATMRECQL | |
| SCHEMBL24629299 | 0.78 | SENP7 (1.00) | GAAMAPTTDP1ATMRECQL | |
| SCHEMBL24629108 | 0.75 | SENP7 (0.71) | GAAMAPTTDP1ATMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240010619-A1 | SMALL MOLECULES WITH ANTIBACTERIAL ACTIVITY | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2024-01-11 | — | — | US | disclosed |
| WO-2022150468-A1 | SMALL MOLECULES WITH ANTIBACTERIAL ACTIVITY | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION (US) | 2022-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240010619-A1 | SMALL MOLECULES WITH ANTIBACTERIAL ACTIVITY | CLPP, MRPL21, TIAL1 | GAA 271/4885MAPT 4374/4885TDP1 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.