Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3674399 | 0.86 | CYP1A2 (0.63) | CYP1A2CYP2C19CYP2C9ALDH1A1LMNA | |
| SCHEMBL10870044 | 0.79 | MAOB (0.56) | MAOAMAOBIDO1S1PR5PPARG | |
| SCHEMBL9242729 | 0.78 | MAOA (0.74) | CYP1A2CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL457634 | 0.78 | MAOA (0.74) | CYP1A2CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL10614200 | 0.77 | TDP1 (0.56) | CYP1A2CYP2C19CYP2C9ALDH1A1LMNA | |
| SCHEMBL2987196 | 0.77 | MAOB (0.54) | MAOAMAOBIDO1S1PR5PPARG | |
| SCHEMBL6446133 | 0.77 | MAOB (0.48) | MAOAMAOBALDH1A1LMNAS1PR5 | |
| SCHEMBL29738633 | 0.77 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP2C9ALDH1A1LMNA | |
| SCHEMBL4639745 | 0.76 | IDO1 (0.73) | MAOAMAOBIDO1S1PR5PPARG | |
| SCHEMBL2056280 | 0.76 | MAOB (0.52) | CYP2C19MAOAMAOBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1240208-A | Process for preparing 3-arylsulfur hydroxamic acids | HOFFMANN LA ROCHE (CH) | 2000-01-05 | — | — | CN | claimed |
| EP-1357109-B1 | Process for aryl alkyl sulfide | HOFFMANN LA ROCHE (CH) | 2008-07-23 | — | — | EP | disclosed |
| EP-1357109-A2 | Process for aryl alkyl sulfide | F. HOFFMANN-LA ROCHE AG (CH) | 2003-10-29 | — | — | EP | disclosed |
| CN-1388117-A | Process for prodcing 3-aryl sulfate iso-hydroximic acid | HOFFMANN LA ROCHE (CH) | 2003-01-01 | — | — | CN | disclosed |
| CN-1240208-A | Process for preparing 3-arylsulfur hydroxamic acids | HOFFMANN LA ROCHE (CH) | 2000-01-05 | — | — | CN | disclosed |
| EP-0965592-A1 | Process for preparing 3-arylsulfur hydroxamic acids | F. HOFFMANN-LA ROCHE AG (CH) | 1999-12-22 | — | — | EP | disclosed |