SCHEMBL457634

SCHEMBL457634

Clc1ccc(Oc2ccc(Cl)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.74
MAOB P27338 1/20 0.74
LMNA P02545 2/20 0.57
CYP2A6 P11509 1/20 0.57
LTA4H P09960 6/20 0.50
ALDH1A1 P00352 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
HPGD P15428 1/20 0.50
CYP2C19 P33261 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
SCN9A Q15858 1/20 0.48
HAO1 Q9UJM8 1/20 0.48
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9242729 1.00 MAOA (0.74) MAOAMAOBLMNACYP2A6LTA4H
SCHEMBL30385926 0.97 MAOA (0.70) MAOAMAOBLMNACYP2A6LTA4H
SCHEMBL9121691 0.91 MAOA (0.64) MAOAMAOBLMNACYP2A6LTA4H
Formaldehyde SCHEMBL28347928 0.91 MAOA (0.64) MAOAMAOBLMNACYP2A6LTA4H
SCHEMBL28996907 0.88 MAOA (0.61) MAOAMAOBLMNACYP2A6LTA4H
SCHEMBL196125 0.88 LTA4H (0.67) MAOAMAOBLTA4HMEN1KMT2A
SCHEMBL7356772 0.86 MAOA (0.58) MAOAMAOBLMNACYP2A6LTA4H
SCHEMBL989610 0.86 MEN1 (0.74) MAOAMAOBLTA4HMEN1KMT2A
SCHEMBL987344 0.86 LTA4H (0.61) MAOAMAOBLTA4HALDH1A1MEN1
SCHEMBL3585620 0.86 MAOA (0.58) MAOAMAOBLMNACYP2A6LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390953-B Method for preparing polyether ketone and product obtained by same 汕头大学 2025-04-04 CN claimed
CN-119751867-A Flame-retardant polyimide resin, polyimide film, and preparation method and application thereof 太湖华强科技有限公司 2025-04-04 CN claimed
CN-119390953-A Method for preparing polyether ketone and product obtained by same 汕头大学 2025-02-07 CN claimed
CN-117105753-A P-chlorobenzene ether compound and preparation method and application thereof 山东则均化学科技有限公司 2023-11-24 CN claimed
CN-116903448-A Method for preparing 3,4' -dichloro diphenyl ether by using difenoconazole waste 浙江宇龙生物科技股份有限公司 2023-10-20 CN claimed
CN-115286493-A Preparation method of 4,4' -diethoxybiphenyl 北京格林凯默科技有限公司 2022-11-04 CN claimed
CN-115261158-A Weakly acidic super-concentrated laundry detergent and preparation method thereof 洋妆源(上海)网络科技有限公司 2022-11-01 CN claimed
CN-114874102-A Method for preparing 4, 4-diaminodiphenyl ether 青岛科技大学 2022-08-09 CN claimed
CN-112300137-B Synthetic method of high-purity difenoconazole 江苏禾本生化有限公司 2022-03-25 CN claimed
CN-113717035-A Recycling method of difenoconazole waste intermediate 江苏禾本生化有限公司 2021-11-30 CN claimed
US-4952665-A Process for production of aromatic polyethers with alkali metal carbonate/bicarbonate/fluoride cocatalyst MITSUBISHI GAS CHEMICAL COMPANY, LTD. (JP) 1990-08-28 US claimed
US-4868275-A POLYTHIOETHERS TOSOH CORPORATION (JP) 1989-09-19 US claimed
US-4845190-A Process for preparing polyarylene sulfides with recovery of carboxylic acid TOSOH CORPORATION (JP) 1989-07-04 US claimed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 EP claimed
EP-0304303-A2 Preparation of poly (arylene sulfide) Tosoh Corporation (JP) 1989-02-22 EP claimed
EP-0275687-A2 Process for preparing polyarylene sulfides Tosoh Corporation (JP) 1988-07-27 EP claimed
EP-0272903-A2 Process for producing a polyarylene sulfide Tosoh Corporation (JP) 1988-06-29 EP claimed
EP-0079144-B1 PROCESS FOR PRODUCING AROMATIC SULFIDE POLYMERS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-01-29 EP claimed
US-4451640-A Process for producing aromatic sulfide polymer KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-05-29 US claimed
EP-0079144-A1 Process for producing aromatic sulfide polymers KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-05-18 EP claimed