Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552020 | 0.89 | LMNA (0.47) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL1946867 | 0.85 | LMNA (0.47) | LMNASMN1; SMN2HPGD | |
| SCHEMBL2333544 | 0.82 | LMNA (0.52) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL1546128 | 0.80 | LMNA (0.46) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL2756837 | 0.77 | LMNA (0.51) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL240142 | 0.77 | LMNA (0.51) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL4639746 | 0.75 | LMNA (0.49) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL2543060 | 0.74 | LMNA (0.45) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL1945158 | 0.74 | LMNA (0.45) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL8188866 | 0.74 | LMNA (0.45) | LMNASMN1; SMN2HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622908-B1 | XANTHINE DERIVATIVES AS A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS INC (US) | 2008-08-06 | — | — | EP | disclosed |